Neurotech Notables #41: October 1-15, 2025

BCI Analysis & Mega Market Activity

Hi Readers,

Time flies until it stops. Rest in peace Nolan Williams.❤️

This issue was intended for last Thursday but I got caught up writing my NYBCI25 Symposium recap. It’ll hit your inbox right here, soon.

Meanwhile, October’s first half has been a parade of big neurotech news:

• Boston Scientific acquired Nalu, while Peter Thiel convinced Histosonics to stay private after last month’s huge acquisition. Funding for consumer wearables, digital Parkinson’s tools, CNS drug discovery platforms, and less-invasive treatment for chronic pain are all important signals for emerging innovations. There’s much more than BCI.

• But also, BCI. Morgan Stanley, whose 2024 outlook report has defined the market for better or worse, dropped a new report that mostly profiles Neuralink, speculating on the AI x BCI x Consumer nexus. The consumer BCI question was a critical theme at NYBCI25, and is the central focus of a new ethics paper linked below.

• Commercial Signal: New companies, products, alliances, partnerships, HQ relocations, executive moves, breakthrough surgeries, & research. But, regulatory news has ground to a halt as the USFG shutdown continues.

• If startup publications are your thing, scroll down for a dozen new company papers, from preprints to peer reviewed journals. If PR is your happy place, check out the shmorgasboard of neurotech on Time’s best inventions list. If you don’t read, then scroll down to Neurotech.TV for some excellent video with investors & CEOs (and maybe…do read )

• What is neurotech’s role in the growing global conversations about brain health, autism, cognition, dementia, psychiatry, and beyond? Check out “Society” for a long roundup of fresh takes, deep reporting, and more.

• New Partnership! I’m thrilled to welcome BrainMind to the Neurotech Futures Ecosystem. Diana and co’s dedication to connecting and supporting leaders is unparalleled. Check out their upcoming NYC event below and stay tuned for more as we move towards next year.

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👋🏽 Hi, I’m Naveen. I believe brain health is human health. You are one of the 3,183 readers of my biweekly reports on emerging neurotech markets.
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Interested in Becoming an Ecosystem Partner? Inquire today.

• NANS: CMS Shutdown: What Physicians Need to Know and Why Advocacy Matters - Read more

• TTP: Why is it so difficult for an implant to talk to a smartphone? Find out what’s really limiting Bluetooth Low Energy connectivity. Discover more

• Datwyler: Why earbuds are in pole position to become the first mainstream platform for EEG acquisition - Learn more

• BrainMind: Brainmind is convening founders, investors, scientists, and artists in NYC on Nov 5 for an intimate salon exploring how AI, neurotech, and psychedelics are redefining the science of the brain and mind. - Apply to attend here

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Funding

• Histosonics closes a $250 million financing from Peter Thiel, Jeff Bezos, others, following $2.25 billion majority acquisition last month (Business Wire | LinkedIn)

• CoMind raises $102.5 million in funding for non-invasive brain monitoring (LinkedIn)

  • What do you know about CoMind? I’m all ears. “Led by Plural with participation from existing investors Angelini Ventures, LocalGlobe, Octopus Ventures, Crane Venture Partners, BACKED VC and Entrepreneurs First. CoMind One is designed to non-invasively measure three physiological parameters simultaneously: cerebral blood flow, cerebral autoregulation, and intracranial pressure.”

• Bexorg raises a $23.5M Series A to transform CNS Drug Development with World’s first Integrated AI and Whole-Human Brain (Bexorg)

• Atlas emerges from stealth with behind-ear wearable, funded with $14m from Acrew Capital, Compound, HOF Capital, Unshackled Ventures, Refactor, Shorewind Capital, and others (LinkedIn)

• Kneu Health Secures $5.6M to Scale Next-Generation Neurology Care (PR Newswire)

• Neuronoff Closes Oversubscribed $4.5M Round to Prepare Launch of Injectrode Platform for Chronic Pain (PR Newswire)

• Ampa wins SBIR grant to support TMS research (LinkedIn)

• Ontario Brain Institute awards $100,000 in non-dilutive funding to HeadFirst, NerView Surgical, Cohesys, Neuropeutics Inc, and Neuro-Mod Inc. (LinkedIn)

• NextSense welcomes QuHarrison Terry to BOD (LinkedIn)

Commercial

• Boston Scientific Announces Agreement to Acquire Nalu Medical, Inc. (Boston Scientific)

  • Boston Scientific expects to complete the transaction in the first half of 2026, subject to customary closing conditions. Nalu is expected to generate sales in excess of $60 million in 2025 and to deliver year-over-year growth in excess of 25% in 2026….*On a 100% basis before consideration of Boston Scientific’s current equity ownership in Nalu Medical, Inc. and other closing adjustments, the transaction price consists of an upfront cash payment of $600 million.

• Cognixion Launches Clinical Trial integrated with Apple Vision Pro (Wired)

  • Nice recap of Cognixion’s rapid milestone stacking by David Fox

• Kernel launches BrainAge, first wellness offering, live in five clinics (Kernel)

• Vivani Medical Withdraws Record Date for Cortigent Neuromodulation Subsidiary Spin-Off (Vivani)

• EpiWatch Announces FDA-Cleared Seizure Detection and Alerting App Now Available for Direct Download (EIN Presswire)

• University at Buffalo (UBNS) Performs First-Ever Outpatient Carotid Stent in an Ambulatory Neurosurgery Center (LinkedIn)

• JOGO Health and SohoMD Partner to Launch Integrated Digital Migraine Care Nationwide (HIT Consultant)

• Cognision and SOMNOmedics Forge Strategic Partnership to Advance Sleep Biomarkers in Pharmaceutical Clinical Trials (PR Newswire)

• Nyxoah Shares Rise on First U.S. Commercial Use of Genio System (Yahoo)

  • A Discussion with Nyxoah’s Leadership (Night Shift)

• Cleveland Clinic and Khosla Ventures Announce Strategic Collaboration (Cleveland Clinic)

  • Here’s hoping this produces more neuro spinouts + portco contracts

• NeuroStim TMS Surpasses 250,000 Treatments, Expands into Minnesota with new Bloomington Clinic (PR Underground)

• CTO Riki Banerjee announces departure from Synchron (LinkedIn)

• Tina Sampath appointed CEO of Cumulus Neuroscience (LinkedIn)

• Subsense hires Michael Nketiah, MBA, RAC as new Senior Vice President of Regulatory & Clinical Trials (LinkedIn)

• Canadian-based medtech company NeuroCatch, Inc. announces U.S. headquarters at Phoenix Bioscience Center (Neurocatch)

• Neuralink Submits Brain Implant Patient Data to Journal (Bloomberg)

• Neuralink Returns to South San Francisco (NeuroFounders)

Regulatory

• FDA’s presence at AdvaMed conference shrinks amid shutdown (MedTechDive)

• Alto Neuroscience Receives FDA Fast Track Designation for ALTO-101 for the Treatment of Cognitive Impairment Associated with Schizophrenia (Alto)

• MindRhythm’s Harmony for Prehospital Large Vessel Occlusion Stroke Identification Submitted for FDA Clearance (Newswires)

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Industry

• Precision: Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation (Nature BME | Business Insider)

  • Precision named to Fast Company’s Next Big Things in Tech List (Globe Newswire)

• NXTSTIM’s EcoAI™ Backed by Largest 24-Month Real-World Dataset in Pain Therapy (EIN Presswire)

• Nexalin Technology Announces Additional Positive Clinical Results in Alzheimer’s Disease with Gen-2 SYNC Neurostimulation Device (Yahoo)

• Forest Neurotech: Functional ultrasound neuroimaging reveals mesoscopic organization of saccades in the lateral intraparietal area (Nature Communications)

• Paradromics: SONIC: A Benchmarking Paradigm for Brain-Computer Interfaces (bioRxiv | blog)

• Spark Biomedical Publishes Peer-Reviewed Trial Showing Wearable Device Reduces Heavy Menstrual Bleeding (Globe Newswire)

• Groundbreaking Study Demonstrates Cala TAPS™ Therapy Reduces Hand Tremor in Essential Tremor Patients by Directly Modulating Brain Activity (PR Newswire)

• E11 Bio Releases PRISM Technology for Self-Correcting Neuron Tracing (E11 | bioRxiv)

• Altoida: Pilot Feasibility Data using Augmented Reality and Machine Learning-Based Digital Cognitive Assessment in Parkinson’s disease (MDS Abstracts)

• Neuropace: Using vision transformers for electrographic seizure classification to aid physician review of intracranial electroencephalography recordings (Human Neurosciences)

• Cost Effectiveness of Adjunctive Neurofeedback vs. Psychotherapy or Pharmacotherapy for Post-Traumatic Stress Disorder (Graymatters)

• X-Nerve: Closed-Loop Vagus Nerve Stimulation Delivered With a Miniaturized System Produces Lasting Recovery in Individuals With Chronic Stroke (American Heart Association)

• UC 1819-backed startup Sense Neuro fueled by $17 million (UCincinnati)

  • Nice profile on ecosystem support, but it does not appear to be new funding.

• Inside the British bet on a ‘live implant’ cure for Parkinson’s (The Times

• How a newly FDA-cleared protocol is expanding access to treatment and simultaneously supporting patient-centered practice growth (Healthcare Business Today)

• Cionic’s Neural sleeve 2: A bionic mobility aid that changes everything (Forbes)

• Neurable opens second round of developer grants (Neurable)

• OpenBCI releases Galea Neon headset (OpenBCI)

• The top BCI stories of 2025 so far (Mass Device)

  • Kudos to these but top ain’t enough. Historic years from Precision, Neuralink, Science, and others.

• Is FNIRS Part of the Future of Precision Psychiatry? (Psychology Today)

• Innovation Across the Lifecycle of Brain Health (EPC)

• Global status report on neurology (WHO)

• Neurotech in Time’s Best Inventions of 2025: Cognixion, HerBrain, SoundHealth Sonnu, Synchron Stentrode, Setpoint System, Medtronic BrainSense aDBS, Ceribell Point-of-Care EEG, Cionic Neural Sleeve 2

📺Neurotech.TV

• Neurotechnology could help billions of people. Has its time come? (WEF)

• Mind the Gap: Funding Emerging Neurotech | LSI Europe ‘25 (LSI)

• We Shall Finally Map The Brain - EP 36 Andrew Payne (Core Memory)

• Natus Neuro’s CEO Chris Landon weighs in on launching strategic partnerships in China (LinkedIn)

• Real Stories, Real People with Dan S. tSCS for SCI (Neurotech Network)

• Beating Depression with Wearable Headset Technology with Erin Lee (MedTech101)

Society

• A Moratorium on Implantable Non-Medical Neurotech Until Effects on the Mind are Properly Understood (Neuroethics | Commentary)

  • BCI & Ethics folks: What do you think about these proposals?

• Neuralink Captures Wall Street’s Eye, Sparks Debate Over Brain Interfaces and Future “Neuro Elite” (Debrief)

• Would You Tell Spotify How You’re Feeling? Exploring Acceptability and Ethics of Emotion-Regulation Plugins for Music Streaming Apps (ACMDL)

• A Path to BCI for All: What do we need to bring human-AI collaboration to nine billion people? (e184)

• The neurosecurity stack: How we balance neurotechnology’s opportunity with security (WEF)

• Autism Is Too Broad (NYTimes) + How Autism Cases Rose as Diagnosis Morphed Over Time (WSJ) + Should the Spectrum Be Split Apart? (NYTimes)

  

  Source: NYTimes

• From Lab to Life: Inside the Institute for Neuroscience, Neurotechnology, and Society (GA Tech)

• Equality & Diversity in Neuroscience (University of Sheffield)

• Sue Goldie Has Parkinson’s Disease (NYTimes)

• Music Conductor Sees Parkinson’s Symptoms Improve With Adaptive Deep Brain Stimulation (Cleveland Clinic)

• When a Hearing Aid Isn’t Enough: More older adults have turned to cochlear implants after Medicare expanded eligibility (NYTimes)

• The U.N. utters the word: Dementia (NPR)

• How Private Equity Oversees the Ethics of Drug Research (NYtimes)

• Silicon Valley Is Investing in the Wrong A.I. (NYTimes)

• Are We Living in a Golden Age of Stupidity? (Guardian)

  • Psst: Don’t let the clickbait title fool you, this essay is a banger and happens to open with neurotech’s role in measuring brainrot.

• Creative experiences and brain clocks (Nature)

Image shared by Augustin Ibanez.

Research

• Parkinson’s disease participant-led research: Towards neuroimaging-assisted deep brain stimulation programming (Journal of PD)

• Eye movements powered by artificial intelligence identify asymptomatic carriers of familial Alzheimer’s disease (Brain Communications)

• Development of a New Around-the-Ear Electroencephalography Device for Passive Brain–Computer Interface Applications (IEEE Sensors Journal)

  

  From IEEE Sensors: “Fabricated ear-EEG device. (a) Initial prototype. (b) Front, (c) back, and (d) side views of the second prototype. In (d), the electrode numbers are specified in the blue circles: 1–3: active, reference, and ground electrodes, respectively. The second prototype was used in the pBCI application experiments.”

• China launches ambitious collaboration to map primate brains—including ours (Science)

• Modulation of poststroke motor cortex activity by metaplasticity-inducted theta burst stimulation: A concurrent TMS-EEG study (Brain Stimulation Journal)

• Innovation in epilepsy care: Alternatives to medication seek to reset, repair brain, expert explains (Mayo Clinic)

• Data-driven fine-grained region discovery in the mouse brain with transformers (Nature Communications | Allen Institute)

• Preclinical Studies Advance Focused Ultrasound for Glioblastoma, Parkinson’s Disease (FUS Foundation)

• Pragmatic Comparative Effectiveness of Primary Care Treatments for Posttraumatic Stress Disorder (Jama Psychiatry)

• Scientists build artificial neurons that work like real ones (Science Daily)

• A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy (Science Advances)

  

  Source: Science

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That’s a wrap! What did I miss? Send news + tips + suggestions for next time.